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What is mifepristone and how does it work?

Mifepristone is a drug that blocks a hormone called progesterone that is needed for a pregnancy to continue. Mifepristone, when used together with another medicine called misoprostol, is used to end an intrauterine pregnancy through ten weeks gestation (70 days or less since the first day of the last menstrual period). The approved mifepristone dosing regimen is:

On day one: 200 mg of mifepristone taken by mouth
24 to 48 hours after taking mifepristone: 800 mcg of misoprostol taken buccally (in the cheek pouch), at a location appropriate for the patient
About seven to fourteen days after taking mifepristone: follow-up with the health care provider
When did the FDA approve mifepristone for medical termination of pregnancy?

The FDA first approved Mifeprex (mifepristone) in September 2000 for medical termination of pregnancy through s…

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